Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase receptor R3' and Ligand = 'BDBM280358'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase receptor R3 (Homo sapiens (Human))	BDBM280358 (4-[[2-(5-chloro-2-fluoro-phenyl)-5-vinyl-4-pyridyl...) Show SMILES CC(C)[C@H](CO)NC(=O)c1cnccc1Nc1cc(ncc1C(C)=C)-c1cc(Cl)ccc1F |r| Show InChI InChI=1S/C25H26ClFN4O2/c1-14(2)18-12-29-22(17-9-16(26)5-6-20(17)27)10-23(18)30-21-7-8-28-11-19(21)25(33)31-24(13-32)15(3)4/h5-12,15,24,32H,1,13H2,2-4H3,(H,31,33)(H,28,29,30)/t24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Medivation Technologies LLC US Patent					Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...				US Patent US10030004 (2018) BindingDB Entry DOI: 10.7270/Q2QC05HQ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase receptor R3 (Homo sapiens (Human))	BDBM280358 (4-[[2-(5-chloro-2-fluoro-phenyl)-5-vinyl-4-pyridyl...) Show SMILES CC(C)[C@H](CO)NC(=O)c1cnccc1Nc1cc(ncc1C(C)=C)-c1cc(Cl)ccc1F |r| Show InChI InChI=1S/C25H26ClFN4O2/c1-14(2)18-12-29-22(17-9-16(26)5-6-20(17)27)10-23(18)30-21-7-8-28-11-19(21)25(33)31-24(13-32)15(3)4/h5-12,15,24,32H,1,13H2,2-4H3,(H,31,33)(H,28,29,30)/t24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q24M98N9
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase receptor R3 (Homo sapiens (Human))	BDBM280358 (4-[[2-(5-chloro-2-fluoro-phenyl)-5-vinyl-4-pyridyl...) Show SMILES CC(C)[C@H](CO)NC(=O)c1cnccc1Nc1cc(ncc1C(C)=C)-c1cc(Cl)ccc1F |r| Show InChI InChI=1S/C25H26ClFN4O2/c1-14(2)18-12-29-22(17-9-16(26)5-6-20(17)27)10-23(18)30-21-7-8-28-11-19(21)25(33)31-24(13-32)15(3)4/h5-12,15,24,32H,1,13H2,2-4H3,(H,31,33)(H,28,29,30)/t24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W380HG
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase receptor R3 (Homo sapiens (Human))	BDBM280358 (4-[[2-(5-chloro-2-fluoro-phenyl)-5-vinyl-4-pyridyl...) Show SMILES CC(C)[C@H](CO)NC(=O)c1cnccc1Nc1cc(ncc1C(C)=C)-c1cc(Cl)ccc1F |r| Show InChI InChI=1S/C25H26ClFN4O2/c1-14(2)18-12-29-22(17-9-16(26)5-6-20(17)27)10-23(18)30-21-7-8-28-11-19(21)25(33)31-24(13-32)15(3)4/h5-12,15,24,32H,1,13H2,2-4H3,(H,31,33)(H,28,29,30)/t24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Medivation Technologies LLC US Patent					Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...				US Patent US10501436 (2019) BindingDB Entry DOI: 10.7270/Q20867PH
					More data for this Ligand-Target Pair