BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine-protein kinase ATM' and Ligand = 'BDBM50535982'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine-protein kinase ATM


(Homo sapiens (Human))		BDBM50535982
PNG
(CHEMBL4567042)
Show SMILES CCC(CC)CNc1c(cnc2ccc(cc12)-c1ccc(C)nc1)C(N)=O
Show InChI InChI=1S/C22H26N4O/c1-4-15(5-2)11-26-21-18-10-16(17-7-6-14(3)24-12-17)8-9-20(18)25-13-19(21)22(23)27/h6-10,12-13,15H,4-5,11H2,1-3H3,(H2,23,27)(H,25,26)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 50n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of ATM phosphorylation at Ser-1981 residue in human HT-29 cells incubated for 1 hr followed by X-ray irradiation by Hoechst staining based...

J Med Chem 59: 6281-92 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00519
BindingDB Entry DOI: 10.7270/Q2NV9NR8
More data for this
Ligand-Target Pair