Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Short transient receptor potential channel 5 (Homo sapiens (Human)) | BDBM50529422 (CHEMBL4447753) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Goldfinch Bio Inc. Curated by ChEMBL | Assay Description Inhibition of (-)-Englerin-activated human TRPC5 channel expressed in HEK293 cells measured at holding potential of -60 mV by Q-patch clamp assay | ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Short transient receptor potential channel 5 (Homo sapiens (Human)) | BDBM50529422 (CHEMBL4447753) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Goldfinch Bio Inc. Curated by ChEMBL | Assay Description Inhibition of lanthanum-activated human TRPC5 channel expressed in HEK293 cells measured at holding potential of -60 mV by Q-patch clamp assay | ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Short transient receptor potential channel 5 (Homo sapiens (Human)) | BDBM50529422 (CHEMBL4447753) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Goldfinch Bio Inc. Curated by ChEMBL | Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol... | ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Short transient receptor potential channel 5 (Homo sapiens (Human)) | BDBM50529422 (CHEMBL4447753) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Goldfinch Bio Inc. Curated by ChEMBL | Assay Description Inhibition of riluzole-activated human TRPC5 channel expressed in HEK293 cells measured at holding potential of -60 mV by Q-patch clamp assay | ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF | |||||||||||
More data for this Ligand-Target Pair |