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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Short transient receptor potential channel 5' and Ligand = 'BDBM50529444'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Short transient receptor potential channel 5


(Homo sapiens (Human))		BDBM50529444
PNG
(CHEMBL4473064)
Show SMILES FC(F)(F)c1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1C#N
Show InChI InChI=1S/C17H14F3N5O2/c18-17(19,20)13-4-2-1-3-11(13)9-25-6-5-24(10-15(25)26)14-8-22-23-16(27)12(14)7-21/h1-4,8H,5-6,9-10H2,(H,23,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.90E+3n/an/an/an/an/an/a



Goldfinch Bio Inc.

Curated by ChEMBL


Assay Description
Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...

ACS Med Chem Lett 10: 1579-1585 (2019)


Article DOI: 10.1021/acsmedchemlett.9b00430
BindingDB Entry DOI: 10.7270/Q2DN48HF
More data for this
Ligand-Target Pair