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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sigma intracellular receptor 2' and Ligand = 'BDBM50540593'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))		BDBM50540593
PNG
(CHEMBL4640137)
Show SMILES Cc1ccc(CN2CCCN(CC2)C(=O)c2ccc3ccccc3n2)c(C)c1
Show InChI InChI=1S/C24H27N3O/c1-18-8-9-21(19(2)16-18)17-26-12-5-13-27(15-14-26)24(28)23-11-10-20-6-3-4-7-22(20)25-23/h3-4,6-11,16H,5,12-15,17H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 35n/an/an/an/an/an/an/an/a



University of Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]-Di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 120 mins by scintillation counting method

ACS Med Chem Lett 11: 651-656 (2020)


Article DOI: 10.1021/acsmedchemlett.9b00524
BindingDB Entry DOI: 10.7270/Q2ZS3134
More data for this
Ligand-Target Pair