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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sigma non-opioid intracellular receptor 1' and Ligand = 'BDBM50002317'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50002317
PNG
(2-(4-Fluoro-phenyl)-5-[4-(5-fluoro-pyrimidin-2-yl)...)
Show SMILES Fc1ccc(cc1)C(CCCN1CCN(CC1)c1ncc(F)cn1)C#N
Show InChI InChI=1S/C19H21F2N5/c20-17-5-3-15(4-6-17)16(12-22)2-1-7-25-8-10-26(11-9-25)19-23-13-18(21)14-24-19/h3-6,13-14,16H,1-2,7-11H2
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 190n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Displacement of (+)-[3H]-3-PPP from rat cortical sigma site

J Med Chem 35: 4516-25 (1993)


BindingDB Entry DOI: 10.7270/Q2H70GDV
More data for this
Ligand-Target Pair