BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Sigma non-opioid intracellular receptor 1' and Ligand = 'BDBM50010617'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50010617 ((-)-3-(1-Propyl-piperidin-3-yl)-phenol \| (S)-3-(1-...) Show SMILES CCCN1CCC[C@H](C1)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 81: 4983-7 (1984) Article DOI: 10.1073/pnas.81.15.4983 BindingDB Entry DOI: 10.7270/Q2JM284N
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50010617 ((-)-3-(1-Propyl-piperidin-3-yl)-phenol \| (S)-3-(1-...) Show SMILES CCCN1CCC[C@H](C1)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									J Pharm Pharmacol 38: 374-9 (1986) Article DOI: 10.1111/j.2042-7158.1986.tb04590.x BindingDB Entry DOI: 10.7270/Q2JS9NXW
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50010617 ((-)-3-(1-Propyl-piperidin-3-yl)-phenol \| (S)-3-(1-...) Show SMILES CCCN1CCC[C@H](C1)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	234	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIDA-IRP Curated by ChEMBL					Assay Description Binding affinity against Sigma receptor type 1 was determined by the displacement of [3H]pentazocine radioligand				J Med Chem 46: 2589-98 (2003) Article DOI: 10.1021/jm030008u BindingDB Entry DOI: 10.7270/Q2H70GJN
NIDA-IRP Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50010617 ((-)-3-(1-Propyl-piperidin-3-yl)-phenol \| (S)-3-(1-...) Show SMILES CCCN1CCC[C@H](C1)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro for binding affinity against sigma receptor using [3H](+)-3-PPP as radioligand				J Med Chem 30: 2169-74 (1988) BindingDB Entry DOI: 10.7270/Q2MW2HQJ
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50010617 ((-)-3-(1-Propyl-piperidin-3-yl)-phenol \| (S)-3-(1-...) Show SMILES CCCN1CCC[C@H](C1)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of (+)-3PPP from sigma receptor of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair