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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sigma non-opioid intracellular receptor 1' and Ligand = 'BDBM50016293'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50016293
PNG
(CHEMBL3262790)
Show SMILES COc1cc2CCN(CCCCNC(=O)c3cc(ccc3OC)-n3cc(CN(C)C)nn3)Cc2cc1OC
Show InChI InChI=1S/C28H38N6O4/c1-32(2)18-22-19-34(31-30-22)23-8-9-25(36-3)24(16-23)28(35)29-11-6-7-12-33-13-10-20-14-26(37-4)27(38-5)15-21(20)17-33/h8-9,14-16,19H,6-7,10-13,17-18H2,1-5H3,(H,29,35)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
 2.24E+4n/an/an/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Displacement of (+)-[3H]pentazocine from sigma-1 receptor in guinea pig brain membrane homogenate after 90 mins by liquid scintillation counting anal...

J Med Chem 57: 4239-51 (2014)


Article DOI: 10.1021/jm5001453
BindingDB Entry DOI: 10.7270/Q20P11KX
More data for this
Ligand-Target Pair