Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sigma non-opioid intracellular receptor 1' and Ligand = 'BDBM50274945'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50274945 (CHEMBL457720 | trans-4-[4-(2-Chlorophenyl)cyclohex...) Show SMILES Clc1ccccc1[C@H]1CC[C@@H](CC1)N1CCN(CC1)c1ccccn1 |r,wU:7.7,wD:10.14,(13.43,1.57,;13.44,.03,;12.11,-.74,;12.11,-2.28,;13.44,-3.05,;14.78,-2.28,;14.77,-.73,;16.1,.05,;16.09,1.59,;17.43,2.36,;18.76,1.59,;18.76,.05,;17.44,-.72,;20.09,2.36,;21.42,1.58,;22.75,2.35,;22.76,3.89,;21.43,4.66,;20.09,3.9,;24.1,4.65,;24.1,6.19,;25.43,6.95,;26.77,6.18,;26.76,4.64,;25.42,3.88,)| Show InChI InChI=1S/C21H26ClN3/c22-20-6-2-1-5-19(20)17-8-10-18(11-9-17)24-13-15-25(16-14-24)21-7-3-4-12-23-21/h1-7,12,17-18H,8-11,13-16H2/t17-,18-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane without cerebellum				J Med Chem 51: 7523-31 (2009) Article DOI: 10.1021/jm800965b BindingDB Entry DOI: 10.7270/Q21837D3
					More data for this Ligand-Target Pair