Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 3' and Ligand = 'BDBM20196'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Signal transducer and activator of transcription 3 (Mus musculus (mouse))	BDBM20196 (3, Ac-pTyr-Leu-Pro-Gln-NH2 | 4-[(2S)-2-{[(2S)-1-[(...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(N)=O |r| Show InChI InChI=1S/C27H41N6O10P/c1-15(2)13-21(27(39)33-12-4-5-22(33)26(38)31-19(24(29)36)10-11-23(28)35)32-25(37)20(30-16(3)34)14-17-6-8-18(9-7-17)43-44(40,41)42/h6-9,15,19-22H,4-5,10-14H2,1-3H3,(H2,28,35)(H2,29,36)(H,30,34)(H,31,38)(H,32,37)(H2,40,41,42)/t19-,20-,21-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	856	n/a	n/a	n/a	n/a	7.5	22
The University of Texas at Houston					Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...				J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM20196 (3, Ac-pTyr-Leu-Pro-Gln-NH2 | 4-[(2S)-2-{[(2S)-1-[(...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(N)=O |r| Show InChI InChI=1S/C27H41N6O10P/c1-15(2)13-21(27(39)33-12-4-5-22(33)26(38)31-19(24(29)36)10-11-23(28)35)32-25(37)20(30-16(3)34)14-17-6-8-18(9-7-17)43-44(40,41)42/h6-9,15,19-22H,4-5,10-14H2,1-3H3,(H2,28,35)(H2,29,36)(H,30,34)(H,31,38)(H,32,37)(H2,40,41,42)/t19-,20-,21-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	856	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas M. D. Anderson Cancer Center Curated by ChEMBL					Assay Description Inhibition of Stat3 (unknown origin) by fluorescence polarization assay				J Med Chem 52: 2429-42 (2009) Article DOI: 10.1021/jm801491w BindingDB Entry DOI: 10.7270/Q28C9W4V
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Mus musculus (mouse))	BDBM20196 (3, Ac-pTyr-Leu-Pro-Gln-NH2 | 4-[(2S)-2-{[(2S)-1-[(...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(N)=O |r| Show InChI InChI=1S/C27H41N6O10P/c1-15(2)13-21(27(39)33-12-4-5-22(33)26(38)31-19(24(29)36)10-11-23(28)35)32-25(37)20(30-16(3)34)14-17-6-8-18(9-7-17)43-44(40,41)42/h6-9,15,19-22H,4-5,10-14H2,1-3H3,(H2,28,35)(H2,29,36)(H,30,34)(H,31,38)(H,32,37)(H2,40,41,42)/t19-,20-,21-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	7.8	22
The University of Texas at Houston					Assay Description His10-Stat3 was expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with 32P...				Bioorg Med Chem Lett 13: 633-6 (2003) Article DOI: 10.1016/S0960-894X(02)01050-8 BindingDB Entry DOI: 10.7270/Q2K35RX1
					More data for this Ligand-Target Pair