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Found 1 hit Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 5B' and Ligand = 'BDBM50034005'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Signal transducer and activator of transcription 5B


(Homo sapiens (Human))
BDBM50034005
PNG
(CHEMBL3358592)
Show SMILES CN(CC(=O)N(Cc1ccc(C)cc1)c1ccc(C(O)=O)c(O)c1)S(=O)(=O)c1c(C)cc(C)cc1C
Show InChI InChI=1S/C27H30N2O6S/c1-17-6-8-21(9-7-17)15-29(22-10-11-23(27(32)33)24(30)14-22)25(31)16-28(5)36(34,35)26-19(3)12-18(2)13-20(26)4/h6-14,30H,15-16H2,1-5H3,(H,32,33)
PDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>6.00E+4n/an/an/an/an/an/an/an/a



University of Toronto Mississauga

Curated by ChEMBL


Assay Description
Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assay


ACS Med Chem Lett 5: 1202-1206 (2014)


Article DOI: 10.1021/ml500165r
BindingDB Entry DOI: 10.7270/Q25X2BJJ
More data for this
Ligand-Target Pair