BindingDB PrimarySearch

Found 11 hits Enz. Inhib. hit(s) with Target = 'Similar to alpha-tubulin isoform 1' and Ligand = 'BDBM50035218'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50035218 (CHEMBL61 \| PODOFILOX \| Podophyllinic acid lactone ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
China Medical College Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 43: 4479-87 (2000) Article DOI: 10.1021/jm000151c BindingDB Entry DOI: 10.7270/Q2JS9T53
China Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50035218 (CHEMBL61 \| PODOFILOX \| Podophyllinic acid lactone ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 37: 3400-7 (1994) Article DOI: 10.1021/jm00046a025 BindingDB Entry DOI: 10.7270/Q2HQ42MX
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50035218 (CHEMBL61 \| PODOFILOX \| Podophyllinic acid lactone ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 40: 3049-56 (1997) Article DOI: 10.1021/jm970146h BindingDB Entry DOI: 10.7270/Q2TQ648T
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50035218 (CHEMBL61 \| PODOFILOX \| Podophyllinic acid lactone ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization (ITP).				J Med Chem 41: 1155-62 (1998) Article DOI: 10.1021/jm9707479 BindingDB Entry DOI: 10.7270/Q2RN3BKW
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50035218 (CHEMBL61 \| PODOFILOX \| Podophyllinic acid lactone ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Concentration inhibiting tubulin polymerization (ITP)				J Med Chem 42: 4081-7 (1999) Article DOI: 10.1021/jm990208z BindingDB Entry DOI: 10.7270/Q2Z60RSS
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50035218 (CHEMBL61 \| PODOFILOX \| Podophyllinic acid lactone ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization measured for 1 hr at 1 min intervals by fluorescence assay				Bioorg Med Chem Lett 24: 3356-60 (2014) Article DOI: 10.1016/j.bmcl.2014.05.096 BindingDB Entry DOI: 10.7270/Q2X068PJ
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50035218 (CHEMBL61 \| PODOFILOX \| Podophyllinic acid lactone ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization by fluorescence analysis				Bioorg Med Chem 22: 5466-75 (2014) Article DOI: 10.1016/j.bmc.2014.07.031 BindingDB Entry DOI: 10.7270/Q25D8TH0
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50035218 (CHEMBL61 \| PODOFILOX \| Podophyllinic acid lactone ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Regensburg Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization using isolated calf brain				J Med Chem 40: 3524-33 (1997) Article DOI: 10.1021/jm970177c BindingDB Entry DOI: 10.7270/Q29S1TRH
Universit£t Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50035218 (CHEMBL61 \| PODOFILOX \| Podophyllinic acid lactone ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization in bovine brain by tubulin assembly assay				J Med Chem 49: 3906-15 (2006) Article DOI: 10.1021/jm060355e BindingDB Entry DOI: 10.7270/Q20004VG
Universit£ di Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50035218 (CHEMBL61 \| PODOFILOX \| Podophyllinic acid lactone ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Ability to inhibit Tubulin polymerization in Bovine brain				J Med Chem 34: 2579-88 (1991) BindingDB Entry DOI: 10.7270/Q2KW5J8Z
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50035218 (CHEMBL61 \| PODOFILOX \| Podophyllinic acid lactone ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibition of purified bovine brain tubulin polymerisation in the absence of microtubule-associated proteins.				Citation and Details BindingDB Entry DOI: 10.7270/Q2PK0J9B
TBA					More data for this Ligand-Target Pair