Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Similar to alpha-tubulin isoform 1 (Bos taurus) | BDBM50060957 (2-Hydroxyestradol 2-methyl ether | 2-methoxy-17bet...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Evaluated for inhibition of tubulin polymerization. | J Med Chem 40: 2323-34 (1997) Article DOI: 10.1021/jm9700833 BindingDB Entry DOI: 10.7270/Q2VQ35CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Similar to alpha-tubulin isoform 1 (Bos taurus) | BDBM50060957 (2-Hydroxyestradol 2-methyl ether | 2-methoxy-17bet...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of tubulin polymerization measured at 12 uM tubulin concentration. | J Med Chem 45: 4748-54 (2002) Article DOI: 10.1021/jm020218r BindingDB Entry DOI: 10.7270/Q29Z97NW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Similar to alpha-tubulin isoform 1 (Bos taurus) | BDBM50060957 (2-Hydroxyestradol 2-methyl ether | 2-methoxy-17bet...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Regensburg Curated by ChEMBL | Assay Description Inhibition of tubulin polymerization using isolated calf brain at 26 degrees C | J Med Chem 40: 3524-33 (1997) Article DOI: 10.1021/jm970177c BindingDB Entry DOI: 10.7270/Q29S1TRH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Similar to alpha-tubulin isoform 1 (Bos taurus) | BDBM50060957 (2-Hydroxyestradol 2-methyl ether | 2-methoxy-17bet...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Regensburg Curated by ChEMBL | Assay Description Inhibition of tubulin polymerization using isolated calf brain | J Med Chem 40: 3524-33 (1997) Article DOI: 10.1021/jm970177c BindingDB Entry DOI: 10.7270/Q29S1TRH | |||||||||||
More data for this Ligand-Target Pair |