Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Similar to alpha-tubulin isoform 1 (Bos taurus) | BDBM50127140![]() ((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | >6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Taiho Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Drug concentration needed to produce a 50% reduction of bovine brain tubulin polymerization relative to the control | J Med Chem 36: 1689-99 (1993) BindingDB Entry DOI: 10.7270/Q2TB194D | |||||||||||
More data for this Ligand-Target Pair |