Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Similar to alpha-tubulin isoform 1' and Ligand = 'BDBM50471429'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50471429 (CHEMBL120152) Show SMILES CCCCC1Cc2cc(O)ccc2-c2c(C=O)c3ccc(O)cc3n12 Show InChI InChI=1S/C21H21NO3/c1-2-3-4-14-9-13-10-15(24)5-7-17(13)21-19(12-23)18-8-6-16(25)11-20(18)22(14)21/h5-8,10-12,14,24-25H,2-4,9H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Regensburg Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization using isolated calf brain				J Med Chem 40: 3524-33 (1997) Article DOI: 10.1021/jm970177c BindingDB Entry DOI: 10.7270/Q29S1TRH
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50471429 (CHEMBL120152) Show SMILES CCCCC1Cc2cc(O)ccc2-c2c(C=O)c3ccc(O)cc3n12 Show InChI InChI=1S/C21H21NO3/c1-2-3-4-14-9-13-10-15(24)5-7-17(13)21-19(12-23)18-8-6-16(25)11-20(18)22(14)21/h5-8,10-12,14,24-25H,2-4,9H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Regensburg Curated by ChEMBL					Assay Description Inhibition of Tubulin polymerization by a 40 uM solution of compound; compound showed inhibition >50% at 40 uM				J Med Chem 41: 4965-72 (1998) Article DOI: 10.1021/jm980228l BindingDB Entry DOI: 10.7270/Q2NV9N0D
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50471429 (CHEMBL120152) Show SMILES CCCCC1Cc2cc(O)ccc2-c2c(C=O)c3ccc(O)cc3n12 Show InChI InChI=1S/C21H21NO3/c1-2-3-4-14-9-13-10-15(24)5-7-17(13)21-19(12-23)18-8-6-16(25)11-20(18)22(14)21/h5-8,10-12,14,24-25H,2-4,9H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Regensburg Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization using isolated calf brain				J Med Chem 40: 3524-33 (1997) Article DOI: 10.1021/jm970177c BindingDB Entry DOI: 10.7270/Q29S1TRH
					More data for this Ligand-Target Pair