Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/calcium exchanger 1' and Ligand = 'BDBM140590'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140590 (US8912224, 19) Show SMILES O=C(Cc1ccccn1)NCc1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C26H23N3O3S/c30-25(15-20-8-4-5-13-27-20)28-16-22-17-29-26(33-22)31-21-10-12-24-19(14-21)9-11-23(32-24)18-6-2-1-3-7-18/h1-8,10,12-14,17,23H,9,11,15-16H2,(H,28,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair