Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/calcium exchanger 1' and Ligand = 'BDBM140619'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140619 (US8912224, 48) Show SMILES O=C(NCc1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1)c1ccno1 Show InChI InChI=1S/C23H19N3O4S/c27-22(21-10-11-26-30-21)24-13-18-14-25-23(31-18)28-17-7-9-20-16(12-17)6-8-19(29-20)15-4-2-1-3-5-15/h1-5,7,9-12,14,19H,6,8,13H2,(H,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
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