Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/calcium exchanger 1' and Ligand = 'BDBM140810'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140810 (US8912224, 245) Show SMILES COC(=O)CNCc1cnc(Oc2ccc3O[C@@H](CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C22H22N2O4S/c1-26-21(25)14-23-12-18-13-24-22(29-18)27-17-8-10-20-16(11-17)7-9-19(28-20)15-5-3-2-4-6-15/h2-6,8,10-11,13,19,23H,7,9,12,14H2,1H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
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