Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/calcium exchanger 1' and Ligand = 'BDBM140830'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140830 (US8912224, 266) Show SMILES OCCNCc1cnc(Oc2ccc3O[C@@H](CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C21H22N2O3S/c24-11-10-22-13-18-14-23-21(27-18)25-17-7-9-20-16(12-17)6-8-19(26-20)15-4-2-1-3-5-15/h1-5,7,9,12,14,19,22,24H,6,8,10-11,13H2/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
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