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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 1' and Ligand = 'BDBM176437'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM176437
PNG
(US9688710, 36 (S,R,S,R,R)-N,N′-((methylazane...)
Show SMILES CS[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(C)c(Cc2ccc(CCCC(=O)NCCCN(C)CCCNC(=O)CCCc3ccc(Cc4cc(ccc4C)[C@@H]4O[C@H](SC)[C@@H](O)[C@H](O)[C@H]4O)cc3)cc2)c1 |r|
Show InChI InChI=1S/C55H75N3O10S2/c1-34-14-24-40(52-48(63)46(61)50(65)54(67-52)69-4)32-42(34)30-38-20-16-36(17-21-38)10-6-12-44(59)56-26-8-28-58(3)29-9-27-57-45(60)13-7-11-37-18-22-39(23-19-37)31-43-33-41(25-15-35(43)2)53-49(64)47(62)51(66)55(68-53)70-5/h14-25,32-33,46-55,61-66H,6-13,26-31H2,1-5H3,(H,56,59)(H,57,60)/t46-,47-,48-,49-,50+,51+,52+,53+,54-,55-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/a7.3n/a



Lexicon Pharmaceuticals, Inc.

US Patent


Assay Description
Human sodium/glucose co-transporter type 1 (SGLT1; accession number NP_000334; GI: 4507031) was cloned into pIRESpuro2 vector for mammalian expressio...

US Patent US9688710 (2017)


BindingDB Entry DOI: 10.7270/Q2154F7P
More data for this
Ligand-Target Pair