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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 1' and Ligand = 'BDBM176440'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium/glucose cotransporter 1


(Homo sapiens (Human))
BDBM176440
PNG
(US9688710, 39 N-(1-amino-2-methyl-1-oxopropan-2-yl...)
Show SMILES CS[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(C)c(Cc2ccc(OCCCC(=O)NC(C)C(N)=O)cc2)c1 |r|
Show InChI InChI=1S/C27H36N2O7S/c1-15-6-9-18(25-23(32)22(31)24(33)27(36-25)37-3)14-19(15)13-17-7-10-20(11-8-17)35-12-4-5-21(30)29-16(2)26(28)34/h6-11,14,16,22-25,27,31-33H,4-5,12-13H2,1-3H3,(H2,28,34)(H,29,30)/t16?,22-,23-,24+,25+,27-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/a7.3n/a



Lexicon Pharmaceuticals, Inc.

US Patent


Assay Description
Human sodium/glucose co-transporter type 1 (SGLT1; accession number NP_000334; GI: 4507031) was cloned into pIRESpuro2 vector for mammalian expressio...


US Patent US9688710 (2017)


BindingDB Entry DOI: 10.7270/Q2154F7P
More data for this
Ligand-Target Pair