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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 1' and Ligand = 'BDBM493891'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM493891
PNG
(US10988462, Example 7)
Show SMILES C[C@@H]1[C@H](CNC1=O)C(=O)Nc1cc(-c2cccc(OC(F)(F)F)c2)n(n1)-c1cncc(c1)C(F)(F)F |r|
Show InChI InChI=1S/C22H17F6N5O3/c1-11-16(10-30-19(11)34)20(35)31-18-7-17(12-3-2-4-15(5-12)36-22(26,27)28)33(32-18)14-6-13(8-29-9-14)21(23,24)25/h2-9,11,16H,10H2,1H3,(H,30,34)(H,31,32,35)/t11-,16+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 17n/an/an/an/an/an/a



Japan Tobacco Inc.

US Patent


Assay Description
Human SGLT1-stably-expressing cell lines were seeded at 5×104 cells/well on BioCoat™ Poly-D-Lysine 96 well plate with Lid (Becton, Dickinson and Comp...

US Patent US10988462 (2021)


BindingDB Entry DOI: 10.7270/Q2TH8QV5
More data for this
Ligand-Target Pair