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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 1' and Ligand = 'BDBM50467842'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM50467842
PNG
(CHEMBL4289746)
Show SMILES Cc1cc(O)c(cc1Cc1ccc(CCCNC(=O)NC(C)(C)CO)cc1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C28H40N2O8/c1-16-11-21(33)20(26-25(36)24(35)23(34)22(14-31)38-26)13-19(16)12-18-8-6-17(7-9-18)5-4-10-29-27(37)30-28(2,3)15-32/h6-9,11,13,22-26,31-36H,4-5,10,12,14-15H2,1-3H3,(H2,29,30,37)/t22-,23-,24+,25-,26+/m1/s1
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Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 30 mins by...

Bioorg Med Chem Lett 28: 3534-3539 (2018)


Article DOI: 10.1016/j.bmcl.2018.09.035
BindingDB Entry DOI: 10.7270/Q2V40XWK
More data for this
Ligand-Target Pair