Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2' and Ligand = 'BDBM176419'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM176419 (US9688710, 18 (S)-2-amino-6-(4-(2-chloro-5-((2S,3R...) Show SMILES CS[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(OCCCC[C@H](N)C(O)=O)cc2)c1 |r| Show InChI InChI=1S/C25H32ClNO7S/c1-35-25-22(30)20(28)21(29)23(34-25)15-7-10-18(26)16(13-15)12-14-5-8-17(9-6-14)33-11-3-2-4-19(27)24(31)32/h5-10,13,19-23,25,28-30H,2-4,11-12,27H2,1H3,(H,31,32)/t19-,20+,21+,22-,23-,25+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.3	n/a
Lexicon Pharmaceuticals, Inc. US Patent					Assay Description Human sodium/glucose co-transporter type 2 (SGLT2; accession number P31639; GI:400337) was cloned into pIRESpuro2 vector for mammalian expression (co...				US Patent US9688710 (2017) BindingDB Entry DOI: 10.7270/Q2154F7P
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