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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2' and Ligand = 'BDBM176424'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM176424
PNG
(US9688710, 23 N-(1,3-dihydroxy-2-(hydroxymethyl)pr...)
Show SMILES CS[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(C)c(Cc2ccc(CCCCC(=O)NC(CO)(CO)CO)cc2)c1 |r|
Show InChI InChI=1S/C29H41NO8S/c1-18-7-12-21(27-25(36)24(35)26(37)28(38-27)39-2)14-22(18)13-20-10-8-19(9-11-20)5-3-4-6-23(34)30-29(15-31,16-32)17-33/h7-12,14,24-28,31-33,35-37H,3-6,13,15-17H2,1-2H3,(H,30,34)/t24-,25-,26+,27+,28-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/a7.3n/a



Lexicon Pharmaceuticals, Inc.

US Patent


Assay Description
Human sodium/glucose co-transporter type 2 (SGLT2; accession number P31639; GI:400337) was cloned into pIRESpuro2 vector for mammalian expression (co...

US Patent US9688710 (2017)


BindingDB Entry DOI: 10.7270/Q2154F7P
More data for this
Ligand-Target Pair