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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2' and Ligand = 'BDBM50161719'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM50161719
PNG
(CHEMBL3785446)
Show SMILES CCOC(=O)CCC(=O)NC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)n1cc(Cc2ccc(cc2)C2CC2)c2c(Cl)cccc12 |r|
Show InChI InChI=1S/C30H35ClN2O7/c1-2-39-25(35)13-12-24(34)32-15-23-27(36)28(37)29(38)30(40-23)33-16-20(26-21(31)4-3-5-22(26)33)14-17-6-8-18(9-7-17)19-10-11-19/h3-9,16,19,23,27-30,36-38H,2,10-15H2,1H3,(H,32,34)/t23-,27-,28+,29-,30-/m1/s1
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n/an/an/an/a 588n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting method

Bioorg Med Chem 24: 2242-50 (2016)


Article DOI: 10.1016/j.bmc.2016.03.058
BindingDB Entry DOI: 10.7270/Q25D8TQP
More data for this
Ligand-Target Pair