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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2' and Ligand = 'BDBM50308529'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM50308529
PNG
(CHEMBL589220 | Methyl (14E)-19-[(benzoyloxy)methyl...)
Show SMILES COC(=O)[C@]1(COC(=O)c2ccccc2)[C@H]2C[C@@H]3N(C\C2=C\C)[C@@H]2C[C@]11c4cc(OC)ccc4N(C)[C@]31O2 |r|
Show InChI InChI=1S/C30H32N2O6/c1-5-18-16-32-24-14-21(18)28(27(34)36-4,17-37-26(33)19-9-7-6-8-10-19)29-15-25(32)38-30(24,29)31(2)23-12-11-20(35-3)13-22(23)29/h5-13,21,24-25H,14-17H2,1-4H3/b18-5-/t21-,24-,25-,28-,29-,30-/m0/s1
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Similars
Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Hoshi University

Curated by ChEMBL


Assay Description
Inhibition of alpha-D-[U-14C]glucopyranoside uptake at human SGLT2 expressed in african green monkey COS1 cells after 30 mins by liquid scintillation...

Bioorg Med Chem 18: 2152-8 (2010)


Article DOI: 10.1016/j.bmc.2010.01.077
BindingDB Entry DOI: 10.7270/Q2HD7VSQ
More data for this
Ligand-Target Pair