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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2' and Ligand = 'BDBM50335135'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM50335135
PNG
(4-Chloro-3-(3-fluoro-4-methoxybenzyl)-1-(beta-D-xy...)
Show SMILES COc1ccc(Cc2cn([C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)c3cccc(Cl)c23)cc1F |r|
Show InChI InChI=1S/C21H21ClFNO5/c1-28-17-6-5-11(8-14(17)23)7-12-9-24(15-4-2-3-13(22)18(12)15)21-20(27)19(26)16(25)10-29-21/h2-6,8-9,16,19-21,25-27H,7,10H2,1H3/t16-,19+,20-,21-/m1/s1
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Similars
Article
PubMed
n/an/an/an/a 473n/an/an/an/a



Taiwan National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...

J Med Chem 54: 166-78 (2011)


Article DOI: 10.1021/jm101072y
BindingDB Entry DOI: 10.7270/Q2445NG8
More data for this
Ligand-Target Pair