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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2' and Ligand = 'BDBM50335140'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM50335140
PNG
(4-Chloro-3-(4-isopropylbenzyl)-1-(beta-D-xylopyran...)
Show SMILES CC(C)c1ccc(Cc2cn([C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)c3cccc(Cl)c23)cc1 |r|
Show InChI InChI=1S/C23H26ClNO4/c1-13(2)15-8-6-14(7-9-15)10-16-11-25(18-5-3-4-17(24)20(16)18)23-22(28)21(27)19(26)12-29-23/h3-9,11,13,19,21-23,26-28H,10,12H2,1-2H3/t19-,21+,22-,23-/m1/s1
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Similars
Article
PubMed
n/an/an/an/a 1.29E+3n/an/an/an/a



Taiwan National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...

J Med Chem 54: 166-78 (2011)


Article DOI: 10.1021/jm101072y
BindingDB Entry DOI: 10.7270/Q2445NG8
More data for this
Ligand-Target Pair