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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2' and Ligand = 'BDBM50335148'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM50335148
PNG
(4-Chloro-3-[4-(prop-2-yn-1-yloxy)benzyl]-1-(beta-D...)
Show SMILES O[C@@H]1CO[C@H]([C@H](O)[C@H]1O)n1cc(Cc2ccc(OCC#C)cc2)c2c(Cl)cccc12 |r|
Show InChI InChI=1S/C23H22ClNO5/c1-2-10-29-16-8-6-14(7-9-16)11-15-12-25(18-5-3-4-17(24)20(15)18)23-22(28)21(27)19(26)13-30-23/h1,3-9,12,19,21-23,26-28H,10-11,13H2/t19-,21+,22-,23-/m1/s1
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Article
PubMed
n/an/an/an/a 530n/an/an/an/a



Taiwan National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...

J Med Chem 54: 166-78 (2011)


Article DOI: 10.1021/jm101072y
BindingDB Entry DOI: 10.7270/Q2445NG8
More data for this
Ligand-Target Pair