Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 3' and Ligand = 'BDBM381666'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 3 (Homo sapiens (Human))	BDBM381666 (US10272079, Compound 23) Show SMILES COCCOCCOCCC(=O)NCCOCCOCCOCCN1CCN(CC1)c1cccc(c1)-c1nc(NC(N)=N)nc2ccc(Cl)cc12 Show InChI InChI=1S/C35H51ClN8O7/c1-46-17-18-50-22-19-47-14-7-32(45)39-8-15-48-20-23-51-24-21-49-16-13-43-9-11-44(12-10-43)29-4-2-3-27(25-29)33-30-26-28(36)5-6-31(30)40-35(41-33)42-34(37)38/h2-6,25-26H,7-24H2,1H3,(H,39,45)(H4,37,38,40,41,42)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.82	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q2251MHH
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Rattus norvegicus)	BDBM381666 (US10272079, Compound 23) Show SMILES COCCOCCOCCC(=O)NCCOCCOCCOCCN1CCN(CC1)c1cccc(c1)-c1nc(NC(N)=N)nc2ccc(Cl)cc12 Show InChI InChI=1S/C35H51ClN8O7/c1-46-17-18-50-22-19-47-14-7-32(45)39-8-15-48-20-23-51-24-21-49-16-13-43-9-11-44(12-10-43)29-4-2-3-27(25-29)33-30-26-28(36)5-6-31(30)40-35(41-33)42-34(37)38/h2-6,25-26H,7-24H2,1H3,(H,39,45)(H4,37,38,40,41,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	135	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q2251MHH
					More data for this Ligand-Target Pair