Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 3' and Ligand = 'BDBM381677'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 3 (Homo sapiens (Human))	BDBM381677 (US10272079, Compound 34) Show SMILES COCCNC(=O)CN(C)CC(=O)NCCOCCOCCNC(=O)NCCOCCOCCOCCOc1ccc(cc1)-c1nc(NC(N)=N)nc2ccc(Cl)cc12 Show InChI InChI=1S/C38H57ClN10O10/c1-49(26-33(50)42-9-13-53-2)27-34(51)43-10-14-54-17-18-55-15-11-44-38(52)45-12-16-56-19-20-57-21-22-58-23-24-59-30-6-3-28(4-7-30)35-31-25-29(39)5-8-32(31)46-37(47-35)48-36(40)41/h3-8,25H,9-24,26-27H2,1-2H3,(H,42,50)(H,43,51)(H2,44,45,52)(H4,40,41,46,47,48)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.31	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q2251MHH
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Rattus norvegicus)	BDBM381677 (US10272079, Compound 34) Show SMILES COCCNC(=O)CN(C)CC(=O)NCCOCCOCCNC(=O)NCCOCCOCCOCCOc1ccc(cc1)-c1nc(NC(N)=N)nc2ccc(Cl)cc12 Show InChI InChI=1S/C38H57ClN10O10/c1-49(26-33(50)42-9-13-53-2)27-34(51)43-10-14-54-17-18-55-15-11-44-38(52)45-12-16-56-19-20-57-21-22-58-23-24-59-30-6-3-28(4-7-30)35-31-25-29(39)5-8-32(31)46-37(47-35)48-36(40)41/h3-8,25H,9-24,26-27H2,1-2H3,(H,42,50)(H,43,51)(H2,44,45,52)(H4,40,41,46,47,48)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q2251MHH
					More data for this Ligand-Target Pair