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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 3' and Ligand = 'BDBM50471803'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/hydrogen exchanger 3


(Oryctolagus cuniculus)		BDBM50471803
PNG
(CHEMBL123859)
Show SMILES [#6]-c1cc2-[#8]-[#6]C([#6])([#6])S(=O)(=O)c2cc1-[#6](=O)\[#7]=[#6](\[#7])-[#7]
Show InChI InChI=1S/C13H17N3O4S/c1-7-4-9-10(5-8(7)11(17)16-12(14)15)21(18,19)13(2,3)6-20-9/h4-5H,6H2,1-3H3,(H4,14,15,16,17)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 36n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes

J Med Chem 41: 3736-47 (1998)


Article DOI: 10.1021/jm981031w
BindingDB Entry DOI: 10.7270/Q2BK1G33
More data for this
Ligand-Target Pair