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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 3' and Ligand = 'BDBM50471822'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/hydrogen exchanger 3


(Oryctolagus cuniculus)		BDBM50471822
PNG
(CHEMBL124826)
Show SMILES NC(=N)NC(=O)c1ccc2CCS(=O)(=O)c2c1
Show InChI InChI=1S/C10H11N3O3S/c11-10(12)13-9(14)7-2-1-6-3-4-17(15,16)8(6)5-7/h1-2,5H,3-4H2,(H4,11,12,13,14)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 790n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes

J Med Chem 41: 3736-47 (1998)


Article DOI: 10.1021/jm981031w
BindingDB Entry DOI: 10.7270/Q2BK1G33
More data for this
Ligand-Target Pair