BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/nucleoside cotransporter 2' and Ligand = 'BDBM50172404'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/nucleoside cotransporter 2


(Homo sapiens (Human))		BDBM50172404
PNG
(CHEMBL3809204)
Show SMILES Nc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NCc3ccc(cc3O)-c3ccccc3)nc12 |r|
Show InChI InChI=1S/C23H24N6O5/c24-20-17-21(27-11-26-20)29(22-19(33)18(32)16(10-30)34-22)23(28-17)25-9-14-7-6-13(8-15(14)31)12-4-2-1-3-5-12/h1-8,11,16,18-19,22,30-33H,9-10H2,(H,25,28)(H2,24,26,27)/t16-,18-,19-,22-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Kissei Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...

J Med Chem 59: 3719-31 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01884
BindingDB Entry DOI: 10.7270/Q2ZW1NT8
More data for this
Ligand-Target Pair