Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/nucleoside cotransporter 2' and Ligand = 'BDBM50172408'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/nucleoside cotransporter 2 (Homo sapiens (Human))	BDBM50172408 (CHEMBL3809978) Show SMILES COc1cc(CNc2nc3c(N)ncnc3n2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)ccc1-c1ccccc1 |r| Show InChI InChI=1S/C24H26N6O5/c1-34-16-9-13(7-8-15(16)14-5-3-2-4-6-14)10-26-24-29-18-21(25)27-12-28-22(18)30(24)23-20(33)19(32)17(11-31)35-23/h2-9,12,17,19-20,23,31-33H,10-11H2,1H3,(H,26,29)(H2,25,27,28)/t17-,19-,20-,23-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...				J Med Chem 59: 3719-31 (2016) Article DOI: 10.1021/acs.jmedchem.5b01884 BindingDB Entry DOI: 10.7270/Q2ZW1NT8
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