Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium/potassium-transporting ATPase subunit alpha-1/beta-1 (Homo sapiens (Human)) | BDBM46355 (DIGOXIN | MLS000069819 | SMR000059217 | US10668094...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 189 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Weizmann Institute of Science | Assay Description Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d... | J Biol Chem 289: 21153-62 (2014) Article DOI: 10.1074/jbc.M114.557629 BindingDB Entry DOI: 10.7270/Q2G44P6T | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-1/beta-1 (Homo sapiens (Human)) | BDBM46355 (DIGOXIN | MLS000069819 | SMR000059217 | US10668094...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars | PDB US Patent | 268 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |