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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 1/10/11/2/3/4/5/8/9 subunit alpha' and Ligand = 'BDBM71352'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 1/10/11/2/3/4/5/8/9 subunit alpha


(Homo sapiens (Human))		BDBM71352
PNG
(US9546164, 423 | US9694002, 423)
Show SMILES Cc1ccc(CN2CCC[C@H](C2)Oc2cc(F)c(cc2C2CC2)C(=O)NS(C)(=O)=O)c(C)c1 |r|
Show InChI InChI=1S/C25H31FN2O4S/c1-16-6-7-19(17(2)11-16)14-28-10-4-5-20(15-28)32-24-13-23(26)22(12-21(24)18-8-9-18)25(29)27-33(3,30)31/h6-7,11-13,18,20H,4-5,8-10,14-15H2,1-3H3,(H,27,29)/t20-/m1/s1
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PC cid
PC sid
UniChem
US Patent
n/an/a 2.10n/an/an/an/a7.425



GENENTECH, INC.; XENON PHARMACEUTICALS INC.

US Patent


Assay Description
Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...

US Patent US9694002 (2017)


BindingDB Entry DOI: 10.7270/Q24B2ZFG
More data for this
Ligand-Target Pair