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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 10 subunit alpha' and Ligand = 'BDBM50497939'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 10 subunit alpha


(Homo sapiens (Human))		BDBM50497939
PNG
(CHEMBL3341974)
Show SMILES CC(C)CC[C@H](N)c1nc2cc(ccc2[nH]1)C(C)(C)C |r|
Show InChI InChI=1S/C17H27N3/c1-11(2)6-8-13(18)16-19-14-9-7-12(17(3,4)5)10-15(14)20-16/h7,9-11,13H,6,8,18H2,1-5H3,(H,19,20)/t13-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 127n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of human Nav1 .8 expressed in HEK cells by PatchXpress electrophysiological assay

Bioorg Med Chem Lett 24: 3690-9 (2014)


Article DOI: 10.1016/j.bmcl.2014.06.038
BindingDB Entry DOI: 10.7270/Q2KS6VJM
More data for this
Ligand-Target Pair