Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 2 subunit alpha' and Ligand = 'BDBM50066425'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066425 (CHEMBL112515 | N,N'-Bis-(4-phenoxy-phenyl)-guanidi...) Show SMILES NC(Nc1ccc(Oc2ccccc2)cc1)=Nc1ccc(Oc2ccccc2)cc1 |w:16.18| Show InChI InChI=1S/C25H21N3O2/c26-25(27-19-11-15-23(16-12-19)29-21-7-3-1-4-8-21)28-20-13-17-24(18-14-20)30-22-9-5-2-6-10-22/h1-18H,(H3,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
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