Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 5 subunit alpha/subunit beta-1/subunit beta-2' and Ligand = 'BDBM50543815'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha/subunit beta-1/subunit beta-2 (Homo sapiens (Human))	BDBM50543815 (CHEMBL4641238) Show SMILES Cc1nsc(NS(=O)(=O)c2cc(F)c(O[C@H]3CCC[C@@H]3c3ccnn3C)cc2F)n1 |r| Show InChI InChI=1S/C18H19F2N5O3S2/c1-10-22-18(29-23-10)24-30(26,27)17-9-12(19)16(8-13(17)20)28-15-5-3-4-11(15)14-6-7-21-25(14)2/h6-9,11,15H,3-5H2,1-2H3,(H,22,23,24)/t11-,15+/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human NaV1.5/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method				J Med Chem 63: 10204-10220 (2020) Article DOI: 10.1021/acs.jmedchem.0c00259 BindingDB Entry DOI: 10.7270/Q2Q52T67
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