Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM275873'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM275873 (US10071957, Example 92) Show SMILES Fc1cc(Oc2cnc(OCC(F)(F)F)c(Cl)c2)c(C=C)cc1C(=O)NS(=O)(=O)N1CCC1 Show InChI InChI=1S/C19H16ClF4N3O5S/c1-2-11-6-13(17(28)26-33(29,30)27-4-3-5-27)15(21)8-16(11)32-12-7-14(20)18(25-9-12)31-10-19(22,23)24/h2,6-9H,1,3-5,10H2,(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	7.2	n/a
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...				US Patent US10071957 (2018) BindingDB Entry DOI: 10.7270/Q2J1056P
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM275873 (US10071957, Example 92) Show SMILES Fc1cc(Oc2cnc(OCC(F)(F)F)c(Cl)c2)c(C=C)cc1C(=O)NS(=O)(=O)N1CCC1 Show InChI InChI=1S/C19H16ClF4N3O5S/c1-2-11-6-13(17(28)26-33(29,30)27-4-3-5-27)15(21)8-16(11)32-12-7-14(20)18(25-9-12)31-10-19(22,23)24/h2,6-9H,1,3-5,10H2,(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.4	25
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Preparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant cell pellets were thawed on ice and diluted to 4 time...				US Patent US10071957 (2018) BindingDB Entry DOI: 10.7270/Q2J1056P
					More data for this Ligand-Target Pair