Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM344698'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM344698 (1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-[2-oxo-2-...) Show SMILES Fc1ccccc1-n1ncc2c(cccc12)N1CCN(CC(=O)N2CCCC2)C1=O Show InChI InChI=1S/C22H22FN5O2/c23-17-6-1-2-7-20(17)28-19-9-5-8-18(16(19)14-24-28)27-13-12-26(22(27)30)15-21(29)25-10-3-4-11-25/h1-2,5-9,14H,3-4,10-13,15H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	805	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9783527 (2017) BindingDB Entry DOI: 10.7270/Q2S184MV
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM344698 (1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-[2-oxo-2-...) Show SMILES Fc1ccccc1-n1ncc2c(cccc12)N1CCN(CC(=O)N2CCCC2)C1=O Show InChI InChI=1S/C22H22FN5O2/c23-17-6-1-2-7-20(17)28-19-9-5-8-18(16(19)14-24-28)27-13-12-26(22(27)30)15-21(29)25-10-3-4-11-25/h1-2,5-9,14H,3-4,10-13,15H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Curated by ChEMBL					Assay Description Inhibition of recombinant human Nav1.7 expressed in HEK293F cells preincubated for 40 mins followed by DiSBAC2 substrate addition measured after 90 m...				J Med Chem 59: 3373-91 (2016) Article DOI: 10.1021/acs.jmedchem.6b00063 BindingDB Entry DOI: 10.7270/Q2C250GW
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM344698 (1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-[2-oxo-2-...) Show SMILES Fc1ccccc1-n1ncc2c(cccc12)N1CCN(CC(=O)N2CCCC2)C1=O Show InChI InChI=1S/C22H22FN5O2/c23-17-6-1-2-7-20(17)28-19-9-5-8-18(16(19)14-24-28)27-13-12-26(22(27)30)15-21(29)25-10-3-4-11-25/h1-2,5-9,14H,3-4,10-13,15H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293F cells measured at -65 mV holding potential by Qpatch clamp method				J Med Chem 59: 3373-91 (2016) Article DOI: 10.1021/acs.jmedchem.6b00063 BindingDB Entry DOI: 10.7270/Q2C250GW
					More data for this Ligand-Target Pair