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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM50545559'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM50545559
PNG
(CHEMBL4642271)
Show SMILES Fc1ccc(cn1)-c1cc(ccc1[C@@H]1CCOc2cc(ccc12)S(=O)(=O)Nc1nccs1)C(F)(F)F |r|
Show InChI InChI=1S/C24H17F4N3O3S2/c25-22-6-1-14(13-30-22)20-11-15(24(26,27)28)2-4-17(20)18-7-9-34-21-12-16(3-5-19(18)21)36(32,33)31-23-29-8-10-35-23/h1-6,8,10-13,18H,7,9H2,(H,29,31)/t18-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

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DrugBank
antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Lupin Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...

J Med Chem 63: 6107-6133 (2020)


Article DOI: 10.1021/acs.jmedchem.0c00361
BindingDB Entry DOI: 10.7270/Q2V69P5C
More data for this
Ligand-Target Pair