BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent betaine transporter' and Ligand = 'BDBM50021360'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium- and chloride-dependent betaine transporter (Mus musculus)	BDBM50021360 (CHEMBL3289575) Show SMILES Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mouse GAT2 expressed in human HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 40 mins by LC-ESI-MS/MS analysi...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113512 BindingDB Entry DOI: 10.7270/Q2R21568
TBA					More data for this Ligand-Target Pair
Sodium- and chloride-dependent betaine transporter (Mus musculus)	BDBM50021360 (CHEMBL3289575) Show SMILES Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Inhibition of mouse GAT2 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake				Eur J Med Chem 83: 256-73 (2014) Article DOI: 10.1016/j.ejmech.2014.06.024 BindingDB Entry DOI: 10.7270/Q21N82P9
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair