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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent betaine transporter' and Ligand = 'BDBM50473306'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent betaine transporter


(Rattus norvegicus)		BDBM50473306
PNG
(CHEMBL556178)
Show SMILES Cl.OC(=O)[C@@H]1CCCN(CCOCCN2c3ccc(F)cc3CCc3cc(F)ccc23)C1 |r|
Show InChI InChI=1S/C24H28F2N2O3.ClH/c25-20-5-7-22-17(14-20)3-4-18-15-21(26)6-8-23(18)28(22)11-13-31-12-10-27-9-1-2-19(16-27)24(29)30;/h5-8,14-15,19H,1-4,9-13,16H2,(H,29,30);1H/t19-;/m1./s1
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 248n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined

J Med Chem 44: 2152-63 (2001)


Article DOI: 10.1021/jm990513k
BindingDB Entry DOI: 10.7270/Q2RB77BX
More data for this
Ligand-Target Pair