Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM141180'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM141180 (US8653100, 91) Show SMILES Cn1cc(cn1)S(=O)(=O)NCc1ccc2CCNC(c2c1)C1(CCC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H27ClN4O2S/c1-29-16-21(15-27-29)32(30,31)28-14-17-3-4-18-9-12-26-23(22(18)13-17)24(10-2-11-24)19-5-7-20(25)8-6-19/h3-8,13,15-16,23,26,28H,2,9-12,14H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US8653100 (2014) BindingDB Entry DOI: 10.7270/Q2JD4VH9
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