Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM141183 (US8653100, 94) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | <100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17... | US Patent US8653100 (2014) BindingDB Entry DOI: 10.7270/Q2JD4VH9 | |||||||||||
More data for this Ligand-Target Pair |