Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM141199'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM141199 (US8653100, 100) Show SMILES Cn1cc(cn1)S(=O)(=O)NCc1ccc2CCNC(c2c1)C(C)(C)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H27ClN4O2S/c1-23(2,18-6-8-19(24)9-7-18)22-21-12-16(4-5-17(21)10-11-25-22)13-27-31(29,30)20-14-26-28(3)15-20/h4-9,12,14-15,22,25,27H,10-11,13H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US8653100 (2014) BindingDB Entry DOI: 10.7270/Q2JD4VH9
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