Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM164685'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164685 (US9067871, 164) Show SMILES COc1cccc(CC2C(CCc3ccc(OCCNS(=O)(=O)c4cn(C)cn4)cc23)N2CCCC2)c1 Show InChI InChI=1S/C28H36N4O4S/c1-31-19-28(29-20-31)37(33,34)30-12-15-36-24-10-8-22-9-11-27(32-13-3-4-14-32)26(25(22)18-24)17-21-6-5-7-23(16-21)35-2/h5-8,10,16,18-20,26-27,30H,3-4,9,11-15,17H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
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